That is important information for all members. Weaker solutions of phenol (25% to 50%) can be used to achieve lighter peels; however, the results are not better than TCA and there is still the risk for systemic toxicity. WILDLIFE TOXICITY ASSESSMENT FOR PHENOL 4 2.3 Summary of Mammalian Toxicity 2.3.1 Mammalian Oral Toxicity 2.3.1.1 Mammalian Oral Toxicity - Acute Oral median lethal doses (LD 50s) for phenol have been given in Lewis (1992), HSDB (2002), and Berman et al. Similarity of these genes with mammalian genes is <50%, and … Mildly acidic, it requires careful handling because it can cause chemical burns. Top Cat. Newer modifications of phenol peels with reduced levels of croton oil have significantly reduced the amount of postoperative hypopigmentation, postoperative erythema, and scarring. Systemic toxicity can result from skin or eye exposures. The onset, severity and duration of toxicity is determined by the dose, route of exposure, physicochemical properties of the organophosphate (e.g. Berje Inc. Where the world comes to its senses : Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals. The higher the concentration of the essential oil (i.e. It is commonly used as a room deodorizer and can be used with other oils for an invigorating massage. Acute keratoconjunctivitis sicca has been reported in some dogs after acetaminophen ingestion. Ingestion of the oil can cause seizures in cats. Phenol has a distinct odor that is sickeningly sweet and tarry. can also undergo several chemical reactions such as . I clean with pine sol and never had a problem with my cats in 12 years. Then, when cats groom, they ingest the cleaner which damages their liver and kidneys. It is a white crystalline solid that is volatile. 1. Cats are more susceptible to salicylate toxicity, because this species is deficient in glucuronidation pathways. All forms of phenol cause irritation, and acute toxic effects of phenol most often occur by skin contact. When compared to dogs, cats are extremely susceptible to phenol toxicity since their liver lacks an important enzyme for metabolism of phenol. Toxicity of flufenamic acid in the cat Toxicity of flufenamic acid in the cat CARLISLE, CAROL H. 1983-10-01 00:00:00 Department of Veterinary Surgery, University of Queensland, St. Lucia, Queensland, 4067, Australia ABSTRACT Twelve cats were treated with dosages of flufenamic acid varying from 80 to 5 mg/kg daily. Oral median lethal doses (LD 50) for phenol are listed in the HSDB [], Lewis [], and Berman et al. Some clinicians believe that for dogs, a starting dose of 0.25 U/kg is appropriate and 0.5 U/kg should be reserved for potentially challenging diabetics. Although not all of these side effects may occur, if they do occur they may need medical attention. Phenol vapor and liquid penetrate the skin with an absorption efficiency approximately equal to the absorption efficiency by inhalation. Cats lack an essential enzyme in their liver and as such have difficulty metabolizing and eliminating certain toxins like essential oils. While most cases 2/7. Cases of toxicosis in this species are most often the result of inappropriate administration. 1961 Feb 15;138:197-9. Glargine (long-acting) Product Description. Examples of such components are phenols. Coal tar: Coal tar is found in products like cresols, creosote, and phenol, and it's included in household disinfectants. Cats are deficient in an enzyme called glucuronyl transferase, which can be found in the liver and is responsible for breaking down Phenol. This essential oil is void of phenol and thus certified safe to diffuse around cats. 2. 22. Berjé is a family-owned business that has been in operation for six decades. The Committee took note of the ADI of 0-0.4 mg/kg bw for 2-phenylphenol (No. Renal injury is also possible. Primarily, the values are clustered in the range 250–500 mg/kg, although the value PMID: 13697246 [PubMed - indexed for MEDLINE] Cats … [8] Spruce Oil. In the case of cats, poisoning happens by absorption through the skin, although ingestion does happen sometimes. I can't find an exact quantity of onions required to cause toxicity problems in dogs, but there are several case reports of onion toxicity and they involve whole onions or sizable portions of chopped onions (like a cup or more). Basically, the higher the concentration of the essential oil (such as one not diffused with carrier oil), the higher the toxicity. Other data on the toxicity of phenol and its derivatives were consistent with the results of the safety evaluation. The cat shows remarkable sensitivity to the adverse effects of phenolic drugs, including acetaminophen and aspirin, as well as structurally-related toxicants found in the diet and environment. Last updated on June 14, 2020 Home ... Cats lack the enzymes in their bodies that break down certain components of essential oils. Cats are probably a little more sensitive to onion toxicity than dogs are. Hot oils like cinnamon, nutmeg, and thyme contain the highest levels of phenol and can be the most offensive to cats. Food poisoning is another common cause of poisoning in cats. Disinfectant toxicity in cats is summarized in table 1. Common drugs such as non-steroidal anti-inflammatories are some of the most deadly to cats. Phenols . Jul 9, 2006 #4 kitytize TCS Member. ERNST MR, KLESMER R, HUEBNER RA, MARTIN JE. This organic compound is present in many essential oils, making them unsafe to use around pets especially cats. The toxicity of phenol . 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